Shanghai Xinzhuang Instrument Co., Ltd. is a leading company in the field of laboratory equipment, committed to technological innovation and excellence in product quality. With a focus on R&D, manufacturing, and sales, the company continuously introduces advanced solutions that support scientific research and development. Their innovative products are designed to meet the evolving needs of researchers worldwide.
One of their standout innovations is the **non-contact automatic ultrasonic cell disruptor**, a cutting-edge device that significantly improves upon traditional methods. Unlike conventional probe-based systems, this instrument eliminates direct contact between the probe and the sample, offering enhanced safety, efficiency, and accuracy. It has gained widespread adoption in research laboratories across Europe and the United States, becoming an essential tool for ChIP (Chromatin Immunoprecipitation) experiments.
Traditional ultrasonic devices often face several limitations. They typically process one sample at a time, require frequent handling of the probe, and may lead to cross-contamination when reusing the same probe for multiple samples. Additionally, variations in probe insertion depth can result in inconsistent energy distribution, affecting the reliability of experimental outcomes. The lack of a closed system also increases the risk of aerosol or foam spread, posing potential biological hazards.
In contrast, the non-contact ultrasonic cell disruptor offers a more efficient and controlled approach. It can process 6 to 12 samples simultaneously, with each sample placed in a fully sealed centrifuge tube to prevent cross-contamination. The use of a 4°C water bath ensures even energy distribution, resulting in consistent and reproducible results. The device allows for flexible parameter settings, making it ideal for standardized experimental procedures.
The working principle of this instrument is truly ingenious. Instead of using a probe, the ultrasonic generator is located at the bottom of the water tank. This design ensures that the entire volume of water is exposed to the ultrasonic waves, creating a uniform and balanced effect. The device also automatically rotates the tubes during the process, further enhancing the evenness of the ultrasonic exposure.
For larger sample volumes, such as 15 ml centrifuge tubes, the system includes a patented resonance mechanism. A metal rod is inserted into the tube, which reflects the ultrasonic waves from the bottom of the tank, amplifying the disruption effect. Importantly, the metal rod does not generate ultrasonic waves directly, avoiding issues like corrosion or damage to the sample.
Overall, the non-contact automatic ultrasonic cell disruptor represents a major advancement in laboratory technology, offering improved safety, efficiency, and precision. Shanghai Xinzhuang Instrument Co., Ltd. continues to innovate and deliver high-quality solutions that empower researchers around the world.
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