Analysis of four estrogen in milk powder by liquid chromatography-mass spectrometry

The content of the four estrogen E1, E2, E3 and EE2 in milk powder was determined by liquid mass spectrometry. Under the best experimental conditions, the results show that the method has a higher recovery rate (60.7-88.4%), a good linear relationship (10-500 ng / mL), high precision (at a lower spiked concentration) The lower RSD is lower than 5.0%) and the low detection limit (1-2.5 ng / mL). For milk powder, the detection limits of the four estrogen E1, E2, E3 and EE2 methods are 0.4? G / kg, 1.0 ?? g / kg, 1.0 ?? g / kg and 1.0 ?? g / kg, respectively. Through the analysis of actual milk powder, the effectiveness of the method is evaluated, and the results are satisfactory. It is suitable for the accurate determination of the content of four estrogen in milk powder, especially the detection of low content samples.


Other,High Quality Other,Other Details, CN


Posted on