Recently, at the Collegiate Inventors Competition held in the United States, the "eye-on-a-chip" technology from the University of Pennsylvania team attracted a lot of attention, despite The first prize of the competition was won by Harvard's 3D bioprinting vascularized human tissue.
The so-called "eye-on-a-chip" refers to the use of chip technology to simulate the function of the human eye. This small plastic chip contains multiple microfluidic channels that have been carefully designed to make corneal cells. It can grow like in the human body. In addition, the students added a click-driven 3D printing eyelid that can be as blinking as the human eye.
According to the research team's website, they can use these microfluidic channels to simulate the human environment and stimulate cell growth. They say the same principle can be applied to different organs on the human body. It was designed by a team of graduate students Cassidy Blundell, Nicholas Perkons and Jeongyun Seo from the School of Applied Science and Engineering at the University of Pennsylvania.
According to Jeongyun Seo, because it can simulate the function of the human eye, it can replace animal or human models for laboratory research. “Our eye-on-a-chip is primarily dedicated to addressing one of the most critical issues in health research: the lack of an effective preclinical model for disease modeling,†he said. “Our devices can be used in many industries. , including drug development, toxicity screening of consumer products.
In this project, the team worked with Dan Huh, a bioengineering expert at the same laboratory, which has been working on the development of synthetic alternatives to biological systems, namely "organ-on-a-chip" ". Although Huh has also developed other organ-on-a-chips before, this time it is a pioneering move to add eye-catching 3D printing to eye-on-a-chip. This eyelid is not designed for fun, it is said to be used in future projects to accurately simulate dry eye syndrome.
However, unfortunately, although the University of Pennsylvania's eye-on-a-chip project is very exciting, it has been robbed of the university inventor competition by Harvard's bioprinting organization project. The inventor of the latter was Harvard's bioengineering doctoral student David Kolesky, who won the first prize for his 3D bioprinting vascularized human tissue and won a $15,000 prize. It is understood that although many people have successfully printed 3D human tissue to date, Kolesky's 3D printing organization is unique in that it can maintain the activity of blood vessels for a long time. The breakthrough significance is not to mention. Yu.
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